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1

Evaluation of Lipid Exposure of Tryptophan Residues in Membrane Peptides and Proteins

Alexey S. Ladokhin

Journal:

Analytical Biochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 84 KB

english, 1999

2

How to Measure and Analyze Tryptophan Fluorescence in Membranes Properly, and Why Bother?

Alexey S. Ladokhin, Sajith Jayasinghe, Stephen H. White

Journal:

Analytical Biochemistry

Année:

2000

Langue:

english

Fichier:

PDF, 176 KB

english, 2000

3

Lifetime fluorescence method for determining membrane topology of proteins

Yevgen O. Posokhov, Alexey S. Ladokhin

Journal:

Analytical Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 176 KB

english, 2006

4

Quenching-enhanced fluorescence titration protocol for accurate determination of free energy of membrane binding

Yevgen O. Posokhov, Philip A. Gottlieb, Alexey S. Ladokhin

Journal:

Analytical Biochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 137 KB

english, 2007

5

A simple “proximity” correction for Förster resonance energy transfer efficiency determination in membranes using lifetime measurements

Yevgen O. Posokhov, Mikhail Merzlyakov, Kalina Hristova, Alexey S. Ladokhin

Journal:

Analytical Biochemistry

Année:

2008

Langue:

english

Fichier:

PDF, 200 KB

english, 2008

6

Steady-state and time-resolved fluorescence quenching with transition metal ions as short-distance probes for protein conformation

Yevgen O. Posokhov, Alexander Kyrychenko, Alexey S. Ladokhin

Journal:

Analytical Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 336 KB

english, 2010

7

Partitioning of 2,6-Bis(1H-Benzimidazol-2-yl)pyridine fluorophore into a phospholipid bilayer: Complementary use of fluorescence quenching studies and molecular dynamics simulations

Alexander Kyrychenko, Igor Yu. Sevriukov, Zoya A. Syzova, Alexey S. Ladokhin, Andrey O. Doroshenko

Journal:

Biophysical Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 989 KB

english, 2011

8

Evidence for an excited-state reaction contributing to NADH fluorescence

Alexey S. Ladokhin, Ludwig Brand

Journal:

Journal of Fluorescence

Année:

1995

Langue:

english

Fichier:

PDF, 727 KB

english, 1995

9

Distribution analysis of membrane penetration of proteins by depth-dependent fluorescence quenching

Alexey S. Ladokhin, P. W. Holloway, E. G. Kostrzhevska

Journal:

Journal of Fluorescence

Année:

1993

Langue:

english

Fichier:

PDF, 247 KB

english, 1993

10

CD Spectroscopy of Peptides and Proteins Bound to Large Unilamellar Vesicles

Alexey S. Ladokhin, Mónica Fernández-Vidal, Stephen H. White

Journal:

Journal of Membrane Biology

Année:

2010

Langue:

english

Fichier:

PDF, 469 KB

english, 2010

11

Membrane Partitioning: “Classical” and “Nonclassical” Hydrophobic Effects

Mónica Fernández-Vidal, Stephen H. White, Alexey S. Ladokhin

Journal:

Journal of Membrane Biology

Année:

2011

Langue:

english

Fichier:

PDF, 497 KB

english, 2011

12

Red-Edge Excitation Study of Nonexponential Fluorescence Decay of Indole in Solution and in a Protein

Alexey S. Ladokhin

Journal:

Journal of Fluorescence

Année:

1999

Langue:

english

Fichier:

PDF, 575 KB

english, 1999

13

Temperature-dependent shift of fluorescence spectra without conformational changes in protein; studies of dipole relaxation in the melittin molecule

Alexander P. Demchenko, Alexey S. Ladokhin

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

1988

Langue:

english

Fichier:

PDF, 833 KB

english, 1988

14

Folding of β-sheet membrane proteins: a hydrophobic hexapeptide model

William C. Wimley, Kalina Hristova, Alexey S. Ladokhin, Loraine Silvestro, Paul H. Axelsen, Stephen H. White

Journal:

Journal of Molecular Biology

Année:

1998

Langue:

english

Fichier:

PDF, 476 KB

english, 1998

15

Folding of amphipathic α-helices on membranes: energetics of helix formation by melittin

Alexey S Ladokhin, Stephen H White

Journal:

Journal of Molecular Biology

Année:

1999

Langue:

english

Fichier:

PDF, 344 KB

english, 1999

16

Protein Chemistry at Membrane Interfaces: Non-additivity of Electrostatic and Hydrophobic Interactions

Alexey S. Ladokhin, Stephen H. White

Journal:

Journal of Molecular Biology

Année:

2001

Langue:

english

Fichier:

PDF, 252 KB

english, 2001

17

Amino acid substitutions in the membrane-binding domain of cytochrome b5 alter its membrane-binding properties

Vera G. Tretyachenko-Ladokhina, Alexey S. Ladokhin, Liming Wang, Alan W. Steggles, Peter W. Holloway

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1993

Langue:

english

Fichier:

PDF, 704 KB

english, 1993

18

Hydrogen-bond energetics drive helix formation in membrane interfaces

Paulo F. Almeida, Alexey S. Ladokhin, Stephen H. White

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2012

Langue:

english

Fichier:

PDF, 465 KB

english, 2012

19

Folding of diphtheria toxin T-domain in the presence of amphipols and fluorinated surfactants: Toward thermodynamic measurements of membrane protein folding

Alexander Kyrychenko, Mykola V. Rodnin, Mauricio Vargas-Uribe, Shivaji K. Sharma, Grégory Durand, Bernard Pucci, Jean-Luc Popot, Alexey S. Ladokhin

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2012

Langue:

english

Fichier:

PDF, 832 KB

english, 2012

20

Folding Amphipathic Helices Into Membranes: Amphiphilicity Trumps Hydrophobicity

Mónica Fernández-Vidal, Sajith Jayasinghe, Alexey S. Ladokhin, Stephen H. White

Journal:

Journal of Molecular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 996 KB

english, 2007

21

Conformational Switching of the Diphtheria Toxin T Domain

Mykola V. Rodnin, Alexander Kyrychenko, Paul Kienker, Onkar Sharma, Yevgen O. Posokhov, R. John Collier, Alan Finkelstein, Alexey S. Ladokhin

Journal:

Journal of Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 796 KB

english, 2010

22

Thermodynamic Measurements of Bilayer Insertion of a Single Transmembrane Helix Chaperoned by Fluorinated Surfactants

Alexander Kyrychenko, Mykola V. Rodnin, Yevgen O. Posokhov, Andrea Holt, Bernard Pucci, J. Antoinette Killian, Alexey S. Ladokhin

Journal:

Journal of Molecular Biology

Année:

2012

Langue:

english

Fichier:

PDF, 668 KB

english, 2012

23

‘Detergent-like’ permeabilization of anionic lipid vesicles by melittin

Alexey S Ladokhin, Stephen H White

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2001

Langue:

english

Fichier:

PDF, 273 KB

english, 2001

24

Evidence for the formation of an unusual ternary complex of rabbit liver EF-1α with GDP and deacylated tRNA

Zoya M. Petrushenko, Boris S. Negrutskii, Alexey S. Ladokhin, Tat'yana V. Budkevich, Vyacheslav F. Shalak, Anna V. El'skaya

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 562 KB

english, 1997

25

Alphas and Taus of Tryptophan Fluorescence in Membranes

Ladokhin, Alexey S., White, Stephen H.

Journal:

Biophysical Journal

Année:

2001

Langue:

english

Fichier:

PDF, 127 KB

english, 2001

26

pH-Triggered Membrane Protein Insertion

Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 37 KB

english, 2011

27

Conformational Switching of the Diphtheria Toxin T-Domain

Rodnin, Mykola V., Kyrychenko, Alexander, Kienker, Paul, Sharma, Onkar, Posokhov, Yevgen O., Collier, R. John, Finkelstein, Alan, Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 43 KB

english, 2011

28

Replacement of C-Terminal Histidines Uncouples Membrane Insertion and Translocation in Diphtheria Toxin T-Domain

Rodnin, Mykola V., Kyrychenko, Alexander, Kienker, Paul, Sharma, Onkar, Vargas-Uribe, Mauricio, Collier, R. John, Finkelstein, Alan, Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 348 KB

english, 2011

29

Bilayer Interactions of Indolicidin, a Small Antimicrobial Peptide Rich in Tryptophan, Proline, and Basic Amino Acids

Ladokhin, Alexey S., Selsted, Michael E., White, Stephen H.

Journal:

Biophysical Journal

Année:

1997

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1997

30

Analysis of Protein and Peptide Penetration into Membranes by Depth-Dependent Fluorescence Quenching: Theoretical Considerations

Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

1999

Langue:

english

Fichier:

PDF, 147 KB

english, 1999

31

Is Lipid Bilayer Binding a Common Property of Inhibitor Cysteine Knot Ion-Channel Blockers?

Posokhov, Yevgen O., Gottlieb, Philip A., Morales, Michael J., Sachs, Frederick, Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

2007

Langue:

english

Fichier:

PDF, 263 KB

english, 2007

32

Interactions of Fluorinated Surfactants with Diphtheria Toxin T-Domain: Testing New Media for Studies of Membrane Proteins

Rodnin, Mykola V., Posokhov, Yevgen O., Contino-Pépin, Christiane, Brettmann, Joshua, Kyrychenko, Alexander, Palchevskyy, Sergiy S., Pucci, Bernard, Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

2008

Langue:

english

Fichier:

PDF, 272 KB

english, 2008

33

FCS Study of the Thermodynamics of Membrane Protein Insertion into the Lipid Bilayer Chaperoned by Fluorinated Surfactants

Posokhov, Yevgen O., Rodnin, Mykola V., Das, Somes K., Pucci, Bernard, Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

2008

Langue:

english

Fichier:

PDF, 206 KB

english, 2008

34

Validation of Depth-Dependent Fluorescence Quenching in Membranes by Molecular Dynamics Simulation of Tryptophan Octyl Ester in POPC Bilayer

Kyrychenko, Alexander, Tobias, Douglas J., Ladokhin, Alexey S.

Journal:

Journal of Physical Chemistry B

Année:

2013

Langue:

english

Fichier:

PDF, 2.72 MB

english, 2013

35

Interfacial Folding and Membrane Insertion of a Designed Helical Peptide †

Ladokhin, Alexey S., White, Stephen H.

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 341 KB

english, 2004

36

Molecular Dynamics Simulations of Depth Distribution of Spin-Labeled Phospholipids within Lipid Bilayer

Kyrychenko, Alexander, Ladokhin, Alexey S.

Journal:

Journal of Physical Chemistry B

Année:

2013

Langue:

english

Fichier:

PDF, 2.33 MB

english, 2013

37

pH-Triggered Conformational Switching of the Diphtheria Toxin T-Domain: The Roles of N-Terminal Histidines

Kurnikov, Igor V., Kyrychenko, Alexander, Flores-Canales, Jose C., Rodnin, Mykola V., Simakov, Nikolay, Vargas-Uribe, Mauricio, Posokhov, Yevgen O., Kurnikova, Maria, Ladokhin, Alexey S.

Journal:

Journal of Molecular Biology

Année:

2013

Langue:

english

Fichier:

PDF, 2.59 MB

english, 2013

38

Reversible Refolding of the Diphtheria Toxin T-Domain on Lipid Membranes †

Ladokhin, Alexey S., Legmann, Rachel, Collier, R. John, White, Stephen H.

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 194 KB

english, 2004

39

Crucial Role of H322 in Folding of the Diphtheria Toxin T-Domain into the Open-Channel State

Vargas-Uribe, Mauricio, Rodnin, Mykola V., Kienker, Paul, Finkelstein, Alan, Ladokhin, Alexey S.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2013

40

Partitioning and Localization of Environment-Sensitive 2-(2′-Pyridyl)- and 2-(2′-Pyrimidyl)-Indoles in Lipid Membranes: A Joint Refinement Using Fluorescence Measurements and Molecular Dynamics Simulations

Kyrychenko, Alexander, Wu, Feiyue, Thummel, Randolph P., Waluk, Jacek, Ladokhin, Alexey S.

Journal:

Journal of Physical Chemistry B

Année:

2010

Langue:

english

Fichier:

PDF, 4.34 MB

english, 2010

41

High-performance time-resolved fluorescence by direct waveform recording

Muretta, Joseph M., Kyrychenko, Alexander, Ladokhin, Alexey S., Kast, David J., Gillispie, Gregory D., Thomas, David D.

Journal:

Review of Scientific Instruments

Année:

2010

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2010

42

Comparison of Membrane Insertion Pathways of the Apoptotic Regulator Bcl-xL and the Diphtheria Toxin Translocation Domain

Vargas-Uribe, Mauricio, Rodnin, Mykola V., Ladokhin, Alexey S.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.79 MB

english, 2013

43

Refining membrane penetration by a combination of steady-state and time-resolved depth-dependent fluorescence quenching

Kyrychenko, Alexander, Ladokhin, Alexey S.

Journal:

Analytical Biochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 925 KB

english, 2014

44

Structural Plasticity in the Topology of the Membrane-Interacting Domain of HIV-1 gp41

Kyrychenko, Alexander, Freites, J. Alfredo, He, Jing, Tobias, Douglas J., Wimley, William C., Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 2.48 MB

english, 2014

45

Measuring membrane penetration with depth-dependent fluorescence quenching: Distribution analysis is coming of age

Ladokhin, Alexey S.

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2014

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2014

46

[Methods in Enzymology] Flourescence Spectroscopy Volume 278 || [22] Distribution analysis of depth-dependent fluorescence quenching in membranes: A practical guide

Ladokhin, Alexey S.

Année:

1997

Langue:

english

Fichier:

PDF, 644 KB

english, 1997

47

[Methods in Enzymology] Flourescence Spectroscopy Volume 278 || [23] Mechanism of leakage of contents of membrane vesicles determined by fluorescence requenching

Ladokhin, Alexey S.

Année:

1997

Langue:

english

Fichier:

PDF, 646 KB

english, 1997

48

Do Acidic Residues in TH8-TH9 Play a Role in Transmembrane Insertion of the Diphtheria Toxin T-Domain?

Ghatak, Chiranjib, Rodnin, Mykola V., Öjemalm, Karin, Holgado, Aurora, Vargas-Uribe, Mauricio, Nilsson, IngMarie, von Heijne, Gunnar, Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 63 KB

english, 2014

49

Kinetic and Thermodynamic Studies of pH-Triggered Membrane Insertion of Diphtheria Toxin T-Domain

Kyrychenko, Alexander, Rodnin, Mykola V., Posokhov, Yevgen O., Thoma, Anna, Brettmann, Joshua, Ladokhin, Alexey S.

Journal:

Biophysical Journal

Année:

2010

Langue:

english

Fichier:

PDF, 32 KB

english, 2010

50

Membrane Association of Diphtheria Toxin T-Domain Characterized by Coarse-Grained and Atomistic Molecular Dynamics Simulations and Experiments

Flores-Canales, Jose C., Vargas-Uribe, Mauricio, Ladokhin, Alexey S., Kurnikova, Maria

Journal:

Biophysical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 42 KB

english, 2013